Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021056 | 0.80 | EP300 (0.51) | CHUKKMT2AMEN1MAPK10KDM4E | |
| SCHEMBL4023758 | 0.77 | CHUK (0.44) | CHUKMAP4K1KMT2AMEN1MAPK10 | |
| SCHEMBL5657826 | 0.75 | RXFP1 (0.45) | CHUKKMT2AMEN1MAPK10KDM4E | |
| SCHEMBL5657172 | 0.74 | RXFP1 (0.64) | CHUKKMT2AMEN1MAPK10EGFR | |
| SCHEMBL14357917 | 0.74 | HDAC1 (0.46) | CHUKKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9426430 | 0.74 | KDM4E (0.50) | CHUKKMT2AMEN1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL29373586 | 0.72 | HDAC1 (0.45) | CHUKKMT2AMEN1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL5749683 | 0.72 | HDAC1 (0.45) | CHUKKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL4019913 | 0.72 | CHUK (0.45) | CHUKMAP4K1MAPK10KDM4EALDH1A1 | |
| SCHEMBL25909532 | 0.71 | RECQL (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |