Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL799396 | 0.79 | LMNA (0.32) | — | |
| SCHEMBL17247519 | 0.78 | USP2 (0.41) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL23541951 | 0.76 | CYP11B2 (0.38) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL24768964 | 0.75 | ESR1 (0.31) | — | |
| SCHEMBL13531018 | 0.74 | ALDH1A1 (0.38) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL8738095 | 0.74 | ALDH1A1 (0.38) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL19380148 | 0.69 | HCAR2 (0.35) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL10496105 | 0.68 | UHRF1 (0.45) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL19453371 | 0.68 | ALDH1A1 (0.34) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL11686432 | 0.67 | ALDH1A1 (0.46) | USP2ALDH1A1GAAPKMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023139534-A1 | SPIROCYCLIC PIPERIDINYL DERIVATIVES AS COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | NOVARTIS AG (CH) | 2023-07-27 | — | — | WO | disclosed |
| EP-3350165-B1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | ORGANOVO INC (US) | 2023-07-26 | — | — | EP | disclosed |