Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25899951 | 0.81 | KMT2A (0.68) | LMNACYP1A2HSD17B10KDM4ENFKB1 | |
| SCHEMBL2546290 | 0.74 | CNR1 (0.51) | — | |
| SCHEMBL12248454 | 0.72 | KMT2A (0.80) | LMNACYP1A2HSD17B10KDM4ENFKB1 | |
| SCHEMBL11788404 | 0.72 | LMNA (0.70) | LMNACYP1A2HSD17B10KDM4ENFKB1 | |
| SCHEMBL10193346 | 0.68 | LMNA (0.49) | LMNACYP1A2HSD17B10KDM4EMEN1 | |
| Trifluoroacetic Acid SCHEMBL12481205 | 0.67 | CFD (0.42) | LMNACYP1A2HSD17B10KDM4ENFKB1 | |
| SCHEMBL13610849 | 0.67 | KMT2A (0.74) | LMNACYP1A2HSD17B10KDM4ENFKB1 | |
| SCHEMBL13967354 | 0.67 | CFD (0.44) | LMNACYP1A2KDM4EMEN1KMT2A | |
| Nalidixic Acid SCHEMBL9743582 | 0.66 | KMT2A (0.97) | LMNACYP1A2HSD17B10KDM4ENFKB1 | |
| SCHEMBL17176644 | 0.66 | HTR3A (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023138362-A1 | WEE1 INHIBITOR, PREPARATION THEREFOR, AND USE THEREOF | 江苏天士力帝益药业有限公司 | 2023-07-27 | — | — | WO | disclosed |