SCHEMBL25900301

SCHEMBL25900301

BC(CCCCCCCC)C(CC)(CC)CC

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.39
LMNA P02545 1/20 0.39
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
DNM1 Q05193 2/20 0.39
TSHR P16473 1/20 0.38
THRB P10828 1/20 0.38
OPRM1 P35372 1/20 0.37
SMPD1 P17405 3/20 0.36
FDPS P14324 3/20 0.35
GPR84 Q9NQS5 2/20 0.35
SPHK1 Q9NYA1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL463961 0.80 DNM1 (0.34) ZDHHC7LCKPPARDZDHHC20ZDHHC2
SCHEMBL3306948 0.71 LMNA (0.39) LMNALCKPPARDZDHHC20ZDHHC2
SCHEMBL28306844 0.71 FDPS (0.44) LMNALCKPPARDZDHHC20ZDHHC2
SCHEMBL3303049 0.71 LMNA (0.39) LMNALCKPPARDZDHHC20ZDHHC2
SCHEMBL17787405 0.71 TSHR (0.50) ZDHHC7LMNALCKPPARDZDHHC20
SCHEMBL22698780 0.71 TSHR (0.50) ZDHHC7LMNALCKPPARDZDHHC20
SCHEMBL14639891 0.71 TSHR (0.50) ZDHHC7LMNALCKPPARDZDHHC20
SCHEMBL14641771 0.71 TSHR (0.50) ZDHHC7LMNALCKPPARDZDHHC20
SCHEMBL19069927 0.71 TSHR (0.50) ZDHHC7LMNALCKPPARDZDHHC20
SCHEMBL8272324 0.71 TSHR (0.50) ZDHHC7LMNALCKPPARDZDHHC20

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241224-A1 2'-ALKYL OR 3'- ALKYL MODIFIED RIBOSE DERIVATIVES AND METHODS OF USE SANEGENE BIO USA INC. 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230241224-A1 2'-ALKYL OR 3'- ALKYL MODIFIED RIBOSE DERIVATIVES AND METHODS OF USE PARP1, PARP2, CD38 ZDHHC7 1880/4885LMNA 180/4885LCK 3635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.