Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22867561 | 0.79 | KISS1R (0.44) | KISS1REPHX1HTR2AHRH1 | |
| SCHEMBL11496923 | 0.77 | DNM1 (0.36) | — | |
| SCHEMBL20903950 | 0.75 | EPHX1 (0.38) | KISS1REPHX1HTR2AHRH1 | |
| SCHEMBL9557352 | 0.73 | OPRM1 (0.42) | — | |
| SCHEMBL18886181 | 0.71 | EPHX1 (0.42) | KISS1REPHX1HTR2AHRH1 | |
| SCHEMBL28668943 | 0.70 | KISS1R (0.40) | KISS1REPHX1HTR2AHRH1 | |
| SCHEMBL15495118 | 0.70 | KISS1R (0.36) | KISS1REPHX1HTR2AHRH1 | |
| SCHEMBL20935089 | 0.68 | HTR2A (0.31) | KISS1RHTR2AHRH1 | |
| SCHEMBL19360522 | 0.68 | — | — | |
| SCHEMBL172994 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241224-A1 | 2'-ALKYL OR 3'- ALKYL MODIFIED RIBOSE DERIVATIVES AND METHODS OF USE | SANEGENE BIO USA INC. | 2023-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230241224-A1 | 2'-ALKYL OR 3'- ALKYL MODIFIED RIBOSE DERIVATIVES AND METHODS OF USE | PARP1, PARP2, CD38 | KISS1R 4601/4885EPHX1 4239/4885HTR2A 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.