Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25900464 | 0.85 | GRM2 (0.32) | GRM2 | |
| SCHEMBL31058433 | 0.84 | LMNA (0.40) | GRM2 | |
| SCHEMBL25898093 | 0.83 | LMNA (0.41) | GRM2 | |
| SCHEMBL25320350 | 0.80 | TIPARP (0.35) | GRM2 | |
| SCHEMBL30550698 | 0.80 | TIPARP (0.35) | GRM2 | |
| Hydrochloric Acid SCHEMBL31058409 | 0.78 | SIK2 (0.38) | GRM2 | |
| Hydrochloric Acid SCHEMBL26658801 | 0.78 | SIK2 (0.38) | GRM2 | |
| SCHEMBL25320140 | 0.77 | TIPARP (0.46) | — | |
| SCHEMBL25320143 | 0.77 | TIPARP (0.46) | — | |
| SCHEMBL25320134 | 0.77 | TIPARP (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |