SCHEMBL2590179

SCHEMBL2590179

Nc1ccc(C(N)c2ccc(N)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.53
MAPT P10636 3/20 0.53
KMT2A Q03164 3/20 0.53
ALDH1A1 P00352 7/20 0.44
CYP3A4 P08684 7/20 0.44
TDP1 Q9NUW8 7/20 0.44
TP53 P04637 2/20 0.44
MAPK1 P28482 4/20 0.40
ALOX15 P16050 3/20 0.40
HSD17B10 Q99714 2/20 0.40
ACHE P22303 1/20 0.40
CA3 P07451 1/20 0.40
THRB P10828 1/20 0.40
CA6 P23280 1/20 0.40
CASP1 P29466 1/20 0.40
HIF1A Q16665 1/20 0.40
CA14 Q9ULX7 1/20 0.40
TSHR P16473 4/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1032680 0.89 DPP4 (0.50) MEN1MAPTKMT2AALDH1A1CYP3A4
Hydrochloric Acid SCHEMBL5403152 0.84 MEN1 (0.38) MEN1MAPTKMT2AALDH1A1CYP3A4
SCHEMBL12461779 0.80 MEN1 (0.53) MEN1MAPTKMT2AALDH1A1CYP3A4
SCHEMBL9663050 0.80 MEN1 (0.53) MEN1MAPTKMT2AALDH1A1CYP3A4
SCHEMBL223522 0.76 MEN1 (0.57) MEN1MAPTKMT2AALDH1A1CYP3A4
SCHEMBL22050356 0.76 MEN1 (0.57) MEN1MAPTKMT2AALDH1A1CYP3A4
SCHEMBL1596487 0.76 MAPT (0.57) MEN1MAPTKMT2AALDH1A1CYP3A4
SCHEMBL6327339 0.75 MEN1 (0.41) MEN1MAPTKMT2AALDH1A1TP53
SCHEMBL342044 0.75 ADRB2 (0.59) MEN1MAPTKMT2AALDH1A1CYP3A4
SCHEMBL22184055 0.75 MAPT (0.47) MEN1MAPTKMT2AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1000108-B1 AQUEOUS POLYIMIDE PROCESS COMMW SCIENT IND RES ORG (AU) 2005-01-05 EP claimed
EP-0577245-B1 Photogenerating azo pigments XEROX CORP (US) 1998-12-02 EP claimed
US-5281503-A Multilayer element with disazo pigments and charge generating layer XEROX CORPORATION (US) 1994-01-25 US claimed
US-4526835-A Prepreg resin sheets formed by impregnating reinforcing substrate with curable polyimide, binding laminated sheets with heat, pressure HITACHI, LTD. (JP) 1985-07-02 US claimed
US-4486583-A MOLDING MATERIALS, COATINGS HITACHI, LTD. (JP) 1984-12-04 US claimed
US-4393188-A PRINTED CIRCUITS HITACHI CHEMICAL COMPANY, LTD. (JP) 1983-07-12 US claimed
US-4283522-A BY HEATING WITH A DIAMINE HITACHI CHEMICAL COMPANY, LTD. (JP) 1981-08-11 US claimed
US-4225498-A Preparation of N-substituted oligo-imides RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US claimed
JP-6128200-A None JP disclosed
US-11965060-B2 Fluorine-containing epoxy resin for electrical materials and method for manufacturing same DAIKIN INDUSTRIES, LTD. (JP) 2024-04-23 US disclosed
US-20220298294-A1 COMPOSITION, CURABLE COMPOSITION, AND CURED PRODUCT DAIKIN INDUSTRIES, LTD. (JP) 2022-09-22 US disclosed
EP-4053214-A1 COMPOSITION, CURABLE COMPOSITION, AND CURED PRODUCT Daikin Industries, Ltd. (JP) 2022-09-07 EP disclosed
US-11319410-B2 Precursor for polyimide and use thereof ETERNAL MATERIALS CO., LTD. (TW) 2022-05-03 US disclosed
US-20220081507-A1 FLUORINE-CONTAINING EPOXY RESIN FOR ELECTRICAL MATERIALS AND METHOD FOR MANUFACTURING SAME DAIKIN INDUSTRIES, LTD. (JP) 2022-03-17 US disclosed
US-4225498-A Preparation of N-substituted oligo-imides RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US disclosed
US-4225497-A ACID CATALYSTS FOR IMIDATION RHONE-POULENC INDUSTRIES (FR) 1980-09-30 US disclosed
US-RE30351-E Aromatic polyimide, polyester and polyamide separation membranes E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-29 US disclosed
US-4113628-A SEMIPERMEABLE, FOR USE IN OSMOSIS, DIALYSIS, ELECTRODIALYSIS, AND REVERSE OSMOSIS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-09-12 US disclosed
US-4107142-A FROM DIENE, ELECTRON DONOR, POLYEPOXIDE, ACRYLONITRILE NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1978-08-15 US disclosed
US-4035345-A Thermosetting bis-imide compositions RHONE-POULENC S.A. (FR) 1977-07-12 US disclosed