SCHEMBL1032680

SCHEMBL1032680

Nc1ccc(C(N)c2ccccc2)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.50
F2 P00734 1/20 0.50
TSHR P16473 1/20 0.50
CYP3A4 P08684 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
TAAR1 Q96RJ0 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MAPT P10636 5/20 0.42
MAOA P21397 4/20 0.42
MAOB P27338 3/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
HTT P42858 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CYP2D6 P10635 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2590179 0.89 MEN1 (0.53) TSHRCYP3A4TDP1TAAR1HSD17B10
SCHEMBL11480062 0.89 DPP4 (0.61) DPP4F2TSHRTAAR1KDM4E
SCHEMBL11478580 0.89 DPP4 (0.61) DPP4F2TSHRTAAR1KDM4E
Aminodiphenylmethane SCHEMBL7841 0.86 DPP4 (0.65) DPP4F2TSHRTAAR1KDM4E
Aminodiphenylmethane SCHEMBL6970159 0.83 DPP4 (0.61) DPP4F2TSHRTAAR1KDM4E
Aminodiphenylmethane SCHEMBL1764753 0.83 DPP4 (0.61) DPP4F2TAAR1ALDH1A1KDM4E
Aminodiphenylmethane SCHEMBL9596876 0.83 DPP4 (0.61) DPP4F2TSHRTAAR1KDM4E
Aminodiphenylmethane SCHEMBL2408346 0.83 DPP4 (0.61) DPP4F2TSHRTAAR1KDM4E
Aminodiphenylmethane SCHEMBL8518249 0.83 DPP4 (0.61) DPP4F2TSHRTAAR1KDM4E
Aminodiphenylmethane SCHEMBL8686295 0.83 DPP4 (0.61) DPP4F2TSHRTAAR1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178717-A Preparation of modified bismaleimide resin 华东理工大学 2023-05-30 CN claimed
CN-112724900-B Tough epoxy resin adhesive and preparation method thereof 台州腾标电子有限公司 2022-08-12 CN claimed
CN-112724900-A Tough epoxy resin adhesive and preparation method thereof 台州腾标电子有限公司 2021-04-30 CN claimed
CN-108325400-B Preparation method of layer-by-layer self-assembled hollow fiber forward osmosis membrane 陕西省膜分离技术研究院有限公司 2020-06-05 CN claimed
EP-3763805-B1 GREASE COMPOSITION NIPPON GREASE CO LTD (JP) 2024-06-12 EP disclosed
CN-116925423-A Chopped carbon fiber and preparation method and application thereof 中国石油化工股份有限公司 2023-10-24 CN disclosed
CN-116589678-A Polyimide precursor composition and polyimide film prepared by using same SK新技术株式会社 2023-08-15 CN disclosed
US-11697786-B2 Grease composition NIPPON GREASE CO., LTD. (JP) 2023-07-11 US disclosed
CN-116178717-A Preparation of modified bismaleimide resin 华东理工大学 2023-05-30 CN disclosed
CN-115991874-A Composition comprising polyamideimide precursor or polyamideimide and polyamideimide film prepared using the same SK新技术株式会社 2023-04-21 CN disclosed
CN-115210314-A Fluorine-containing copolymer composition 关东电化工业株式会社 2022-10-18 CN disclosed
CN-112724900-B Tough epoxy resin adhesive and preparation method thereof 台州腾标电子有限公司 2022-08-12 CN disclosed
US-4371686-A POLYETHERURETHANE COPOLYMER AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY MINISTRY OF INTERNATIONAL TRADE & INDUSTRY (JP) 1983-02-01 US disclosed
US-4360543-A WITH HARDENABLE POLYESTERIMIDE DR. BECK & CO. AG (DE) 1982-11-23 US disclosed
US-4348511-A POLYURETHANES MODIFIED WITH BETA-AMINOCROTONIC ACID DERIVATIVES CIBA-GEIGY CORPORATION (US) 1982-09-07 US disclosed
EP-0039663-A2 Process for preparing crosslinked saturated polymers, and these polymers CIBA-GEIGY AG (CH) 1981-11-11 EP disclosed
US-4284752-A Process for producing crosslinked unsaturated polymers by reaction of .beta. CIBA-GEIGY CORPORATION (US) 1981-08-18 US disclosed
US-4239814-A Method of producing electrically insulating, highly flexible and/or solderable coatings HERBERTS GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1980-12-16 US disclosed
US-4033820-A Starch sponge column apparatus and process for immobilized enzyme reactions PENICK & FORD, LIMITED (US) 1977-07-05 US disclosed
US-4013511-A HYDROPHILIC POLYMERIC CARRIER FROM ETHYLENE-MALEIC ANHYDRIDE COPOLYMER AND DIAMINE YEDA RESEARCH & DEVELOPMENT CO. LTD. (IL) 1977-03-22 US disclosed