Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 4/20 | 0.47 |
| ▸ | MMP8 | P22894 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25314534 | 0.88 | MMP1 (0.47) | MMP1TSHRCA12CA1CA2 | |
| SCHEMBL25902130 | 0.85 | TDP1 (0.51) | MMP1TSHRCA12CA1CA2 | |
| SCHEMBL7208418 | 0.84 | MMP1 (0.63) | MMP1TSHRCA12CA1CA2 | |
| SCHEMBL7207812 | 0.84 | MMP13 (0.69) | MMP1TSHRCA12CA1CA2 | |
| SCHEMBL15060917 | 0.83 | CA12 (0.70) | MMP1TSHRCA12CA1CA2 | |
| SCHEMBL5388006 | 0.82 | MMP1 (0.61) | MMP1TSHRCA12CA1CA2 | |
| SCHEMBL5384277 | 0.82 | MMP1 (0.61) | MMP1TSHRCA12CA1CA2 | |
| SCHEMBL8798490 | 0.81 | CA12 (0.58) | MMP1TSHRCA12CA1CA2 | |
| SCHEMBL6743970 | 0.81 | TSHR (0.68) | MMP1TSHRCA12CA1CA2 | |
| SCHEMBL13527221 | 0.80 | TSHR (0.66) | MMP1TSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141432-A2 | APOL1 INHIBITORS AND METHODS OF USE | MAZE THERAPEUTICS, INC. (US) | 2023-07-27 | — | — | WO | disclosed |