Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA7 | P43166 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | MMP1 | P03956 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MMP13 | P45452 | 3/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | NQO1 | P15559 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20054093 | 0.84 | MMP13 (0.72) | MMP1ALDH1A1MMP13MMP8MMP9 | |
| SCHEMBL25901928 | 0.81 | MMP1 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7207812 | 0.81 | MMP13 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7208418 | 0.81 | MMP1 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11326336 | 0.80 | CA12 (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL15060917 | 0.79 | CA12 (0.70) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18551235 | 0.79 | CA12 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5384277 | 0.79 | MMP1 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL19389534 | 0.79 | MMP13 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5388006 | 0.79 | MMP1 (0.61) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561738-B1 | Fluoran colour-formers | CIBA GEIGY (CH) | 1997-06-04 | — | — | EP | disclosed |
| US-5395948-A | Colorfastness; migration and sublimation stability; heat and pressure sensitive recording materials | CIBA-GEIGY CORPORATION (US) | 1995-03-07 | — | — | US | disclosed |
| EP-0561738-A1 | Fluoran colour-former | CIBA-GEIGY AG (CH) | 1993-09-22 | — | — | EP | disclosed |