Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 6/20 | 0.43 |
| ▸ | KIT | P10721 | 3/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 4/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25902165 | 0.86 | TIPARP (0.54) | TIPARPKITLCKSRCKDR | |
| SCHEMBL25900117 | 0.85 | TIPARP (0.46) | TIPARP | |
| SCHEMBL25907752 | 0.85 | TIPARP (0.53) | TIPARPKITLCKSRCKDR | |
| SCHEMBL25899525 | 0.84 | TIPARP (0.44) | TIPARPHTR1AHTR2ADRD2FLT3 | |
| SCHEMBL25900208 | 0.84 | TIPARP (0.54) | TIPARPKITLCKSRCKDR | |
| SCHEMBL26793446 | 0.84 | TIPARP (0.49) | TIPARP | |
| SCHEMBL25897832 | 0.83 | TIPARP (0.49) | TIPARP | |
| SCHEMBL25907905 | 0.83 | ACHE (0.39) | DRD2ACHEHCRTR1 | |
| SCHEMBL25323238 | 0.82 | TIPARP (0.48) | TIPARPKITHTR1AHTR2ADRD2 | |
| SCHEMBL30550691 | 0.82 | TIPARP (0.48) | TIPARPKITHTR1AHTR2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |