Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.34 |
| ▸ | EIF4EBP1 | Q13541 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25908034 | 0.90 | DRD2 (0.40) | ACHEDRD2DRD5DRD3GRK2 | |
| SCHEMBL25907670 | 0.89 | ACHE (0.41) | ACHELMNATSHRHTTNPSR1 | |
| SCHEMBL25907918 | 0.85 | TIPARP (0.40) | ACHELMNATSHRHTTNPSR1 | |
| SCHEMBL25902177 | 0.83 | TIPARP (0.43) | ACHEDRD2HCRTR1 | |
| SCHEMBL25901097 | 0.82 | NPC1 (0.41) | DRD2DRD5DRD3DDR1HTR7 | |
| SCHEMBL25907928 | 0.79 | ACHE (0.36) | ACHELMNATSHRHTTNPSR1 | |
| SCHEMBL25908025 | 0.79 | EIF4EBP1 (0.39) | ACHEDRD2DRD5DRD3GRK2 | |
| SCHEMBL25321300 | 0.79 | TIPARP (0.40) | HCRTR1 | |
| SCHEMBL30550839 | 0.79 | TIPARP (0.40) | HCRTR1 | |
| SCHEMBL30550931 | 0.78 | TIPARP (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |