Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.41 |
| ▸ | GRK2 | P25098 | 2/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 2/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8351342 | 0.81 | HDAC6 (0.44) | EIF4EBP1GRK2DDR1RAB9AHDAC6 | |
| SCHEMBL25907670 | 0.81 | ACHE (0.41) | EIF4EBP1GRK2DDR1 | |
| SCHEMBL25908025 | 0.80 | EIF4EBP1 (0.39) | EIF4EBP1GRK2TNF | |
| SCHEMBL25901097 | 0.76 | NPC1 (0.41) | DDR1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL25899259 | 0.74 | NPC1 (0.42) | EIF4EBP1GRK2RAB9AHDAC6NPC1 | |
| SCHEMBL25912391 | 0.74 | CYP11B2 (0.39) | EIF4EBP1GRK2DDR1RAB9ANPC1 | |
| SCHEMBL25899268 | 0.74 | NPC1 (0.41) | GRK2RAB9AHDAC6NPC1ALDH1A1 | |
| SCHEMBL31362805 | 0.73 | TIPARP (0.64) | — | |
| SCHEMBL31123009 | 0.72 | HDAC6 (0.40) | GRK2DDR1RAB9AHDAC6NPC1 | |
| SCHEMBL24754381 | 0.72 | DDR1 (0.54) | GRK2DDR1RAB9ASTAT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |