Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | EIF4EBP1 | Q13541 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GRK2 | P25098 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.34 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.33 |
| ▸ | USP19 | O94966 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25908025 | 0.90 | EIF4EBP1 (0.39) | ACHEEIF4EBP1GRK2 | |
| SCHEMBL25907905 | 0.89 | ACHE (0.39) | ACHEEIF4EBP1LMNATSHRHTT | |
| SCHEMBL25907918 | 0.82 | TIPARP (0.40) | ACHEEIF4EBP1LMNATSHRHTT | |
| SCHEMBL25904008 | 0.81 | EIF4EBP1 (0.41) | EIF4EBP1GRK2DDR1 | |
| SCHEMBL25908034 | 0.79 | DRD2 (0.40) | ACHEEIF4EBP1GRK2DDR1 | |
| SCHEMBL25908014 | 0.78 | TIPARP (0.39) | ACHEEIF4EBP1GRK2 | |
| SCHEMBL25907877 | 0.77 | TIPARP (0.44) | ACHEEIF4EBP1GRK2 | |
| SCHEMBL25320462 | 0.77 | TIPARP (0.42) | EIF4EBP1GRK2 | |
| SCHEMBL25907928 | 0.76 | ACHE (0.36) | ACHELMNATSHRHTTNPSR1 | |
| SCHEMBL25899268 | 0.74 | NPC1 (0.41) | LMNATSHRNPSR1GRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |