Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAP2 | P11137 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25903697 | 0.78 | PDE3B (0.56) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL25904127 | 0.76 | PDE3B (0.50) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL3280681 | 0.75 | PDE3B (0.52) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL25904140 | 0.74 | PRKAB2 (0.50) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL28445737 | 0.72 | KDM4E (0.71) | KDM4EALDH1A1HPGDSMN1; SMN2MEN1 | |
| SCHEMBL11601027 | 0.70 | PTGS2 (0.42) | KDM4EHPGDMEN1KMT2AMAPT | |
| SCHEMBL12686439 | 0.69 | CYP1A2 (0.51) | KDM4EPOLB | |
| SCHEMBL8784597 | 0.68 | CYP1A2 (0.74) | KDM4EMEN1KMT2AHSD17B10POLB | |
| SCHEMBL25904278 | 0.68 | CHEK1 (0.45) | PDE3BPDE3AKDM4EALDH1A1HPGD | |
| SCHEMBL1082799 | 0.68 | MAPT (0.56) | PDE3BPDE3AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147513-A2 | COMPOSITIONS OF AUTOPHAGY MODULATING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2023-08-03 | — | — | WO | disclosed |