Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 3/20 | 0.50 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.50 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.50 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.50 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.50 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.50 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | F11 | P03951 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25904284 | 0.84 | KDM4E (0.47) | PDE3BPDE3ACA2MAOBLMNA | |
| SCHEMBL4551905 | 0.80 | PTGS2 (0.47) | LMNAF11MEN1KMT2A | |
| SCHEMBL15300814 | 0.78 | MEN1 (0.54) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL1082799 | 0.78 | MAPT (0.56) | PDE3BPDE3ALMNAKDM4EALDH1A1 | |
| SCHEMBL8925407 | 0.78 | CA1 (0.53) | CA2CA1MAOBPDGFRBFLT3 | |
| SCHEMBL4552979 | 0.77 | KDM4E (0.47) | LMNAKDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL24638108 | 0.76 | F11 (0.50) | CA1LMNAALDH1A1HPGDMAPT | |
| SCHEMBL705545 | 0.75 | KDM4E (0.59) | PDE3BPDE3ACA2CA1MAOB | |
| SCHEMBL25904148 | 0.74 | PDE3B (0.50) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL878695 | 0.74 | CA12 (0.59) | PDE3BPDE3ACA2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147513-A2 | COMPOSITIONS OF AUTOPHAGY MODULATING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2023-08-03 | — | — | WO | disclosed |