Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | WEE1 | P30291 | 2/20 | 0.38 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25904278 | 0.81 | CHEK1 (0.45) | TNKS2PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL25903699 | 0.80 | PDE3B (0.55) | PDE3BPDE3AMEN1KMT2AHTT | |
| SCHEMBL25904303 | 0.79 | F11 (0.50) | PDE3BPDE3AMEN1KMT2ADAO | |
| SCHEMBL25904763 | 0.77 | MEN1 (0.58) | TNKS2PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL25905198 | 0.77 | PDE3B (0.41) | TNKS2PDE3BPDE3AMEN1KMT2A | |
| SCHEMBL2957821 | 0.76 | F11 (0.46) | PDE3BPDE3AMEN1KMT2ARXFP1 | |
| SCHEMBL25904145 | 0.74 | CNR1 (0.40) | PDE3BPDE3AMEN1KMT2ARXFP1 | |
| SCHEMBL25903697 | 0.74 | PDE3B (0.56) | PDE3BPDE3AMEN1KMT2AWEE1 | |
| SCHEMBL25904296 | 0.74 | MAP2 (0.41) | PDE3BPDE3AMEN1KMT2ARXFP1 | |
| SCHEMBL25904123 | 0.73 | KDM4E (0.38) | PDE3BPDE3AMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147513-A2 | COMPOSITIONS OF AUTOPHAGY MODULATING AGENTS AND USES THEREOF | WASHINGTON UNIVERSITY (US) | 2023-08-03 | — | — | WO | disclosed |