Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 13/20 | 0.54 |
| ▸ | TYMS | P04818 | 3/20 | 0.49 |
| ▸ | GART | P22102 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24629143 | 0.92 | DHFR (0.55) | DHFRTYMSGART | |
| SCHEMBL10405409 | 0.86 | DHFR (0.63) | DHFRGART | |
| SCHEMBL24629147 | 0.81 | DHFR (0.61) | DHFR | |
| SCHEMBL12601417 | 0.80 | DHFR (0.59) | DHFRTYMSGART | |
| SCHEMBL9224790 | 0.80 | GART (0.64) | DHFRTYMSGART | |
| SCHEMBL25904701 | 0.79 | DHFR (0.59) | DHFR | |
| SCHEMBL6337570 | 0.79 | DHFR (0.77) | DHFRTYMSGART | |
| SCHEMBL12717676 | 0.78 | DHFR (0.72) | DHFR | |
| SCHEMBL12717668 | 0.78 | DHFR (0.72) | DHFR | |
| SCHEMBL9446115 | 0.77 | DHFR (0.75) | DHFRGART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230226214-A1 | BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION | LYCIA THERAPEUTICS, INC. | 2023-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230226214-A1 | BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION | HAVCR2, FCGR3B, FCGR2A | DHFR 2599/4885TYMS 1616/4885GART 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.