Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 16/20 | 0.43 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25897776 | 0.89 | GRM2 (0.46) | GRM2 | |
| SCHEMBL25898732 | 0.79 | GRM2 (0.51) | GRM2 | |
| SCHEMBL25899525 | 0.77 | TIPARP (0.44) | GRM2HDAC1HDAC8HDAC6HDAC5 | |
| SCHEMBL31058433 | 0.73 | LMNA (0.40) | GRM2 | |
| SCHEMBL25898093 | 0.72 | LMNA (0.41) | GRM2 | |
| SCHEMBL25900478 | 0.71 | GRM2 (0.32) | GRM2 | |
| SCHEMBL25900117 | 0.70 | TIPARP (0.46) | GRM2 | |
| SCHEMBL25900464 | 0.69 | GRM2 (0.32) | GRM2 | |
| Hydrochloric Acid SCHEMBL31058409 | 0.69 | SIK2 (0.38) | GRM2 | |
| Hydrochloric Acid SCHEMBL26658801 | 0.69 | SIK2 (0.38) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |