SCHEMBL25906244

SCHEMBL25906244

COc1c(O)ccc2c1oc1c(OC)c(O)ccc12

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.62
MAOB P27338 1/20 0.57
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA13 Q8N1Q1 2/20 0.55
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
APEX1 P27695 1/20 0.46
RECQL P46063 1/20 0.46
BLM P54132 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9747985 0.81 MAOA (0.65) MAOAMAOBCA12CA1CA7
SCHEMBL9623295 0.79 ESR1 (0.55) MAOAMAOBCA12CA1CA7
SCHEMBL11432556 0.77 MAOA (1.00) MAOAMAOBCA12CA1CA7
SCHEMBL28372652 0.77 MAOA (0.73) MAOAMAOBCA12CA1CA7
SCHEMBL69925 0.75 TDP1 (0.52) MAOAMAOBCA12CA1CA7
SCHEMBL29403778 0.75 TDP1 (0.52) MAOAMAOBCA12CA1CA7
SCHEMBL15211121 0.75 MAOA (0.54) MAOAMAOBCA12CA1CA7
SCHEMBL29808497 0.74 MAOA (0.72) MAOAMAOBMGAMGAASI
SCHEMBL151859 0.73 MAOA (0.71) MAOAMAOBKDM4EMEN1ALDH1A1
SCHEMBL30776625 0.72 HPGD (0.53) MAOAMAOBCA12CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed