Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.65 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25906244 | 0.81 | MAOA (0.62) | MAOAESR2MAOBKDM4EALDH1A1 | |
| SCHEMBL6825266 | 0.79 | ESR2 (1.00) | MAOAESR2KDM4EALDH1A1HPGD | |
| SCHEMBL7987277 | 0.78 | ESR2 (0.70) | MAOAESR2MAOBKDM4EALDH1A1 | |
| SCHEMBL9747411 | 0.78 | MAOA (0.65) | MAOAESR2MAOBKDM4EALDH1A1 | |
| SCHEMBL26766942 | 0.76 | ESR2 (0.66) | ESR2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL29853705 | 0.76 | ESR2 (0.66) | MAOAESR2MAOBKDM4EALDH1A1 | |
| SCHEMBL30629209 | 0.76 | ESR2 (0.66) | ESR2KDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL26766945 | 0.76 | ESR2 (0.66) | MAOAESR2MAOBKDM4EALDH1A1 | |
| SCHEMBL11839158 | 0.75 | ESR2 (0.65) | MAOAESR2MAOBKDM4EALDH1A1 | |
| SCHEMBL9748258 | 0.74 | ESR2 (0.55) | MAOAESR2MAOBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024025953-A2 | THERAPEUTIC USES OF UROLITHIN DERIVATIVES | VANDRIA SA (CH) | 2024-02-01 | — | — | WO | disclosed |
| US-11820751-B2 | Urolithin derivatives and methods of use thereof | VANDRIA SA (CH) | 2023-11-21 | — | — | US | disclosed |
| US-5104894-A | Ellagic acid analogues | UNIVERSITY OF GUELPH (CA) | 1992-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820751-B2 | Urolithin derivatives and methods of use thereof | NLN, UQCRC2, TUFM | MAOA 699/4885ESR2 4060/4885MAOB 590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.