SCHEMBL9623295

SCHEMBL9623295

COc1c(O)ccc2c(OC)c(O)ccc12

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.55
ESR2 Q92731 1/20 0.55
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
MAPK1 P28482 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MAOA P21397 4/20 0.47
TDP1 Q9NUW8 1/20 0.46
HIF1A Q16665 1/20 0.45
EPAS1 Q99814 1/20 0.45
CA1 P00915 3/20 0.44
CA12 O43570 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
CA2 P00918 2/20 0.43
MAOB P27338 2/20 0.43
PPARG P37231 1/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29403778 0.85 TDP1 (0.52) ESR1ESR2KDM4EALDH1A1MAPK1
SCHEMBL69925 0.85 TDP1 (0.52) ESR1ESR2KDM4EALDH1A1MAPK1
SCHEMBL11504661 0.82 HPRT1 (0.52) ESR1ESR2KDM4EALDH1A1MAPK1
SCHEMBL14216852 0.79 MAPK1 (0.42) ESR1ESR2KDM4EALDH1A1MAPK1
SCHEMBL5804536 0.79 ESR1 (0.51) ESR1ESR2KDM4EMAOATDP1
SCHEMBL29770963 0.79 ESR1 (0.51) ESR1ESR2KDM4EMAOATDP1
SCHEMBL9623607 0.79 ESR1 (0.75) ESR1ESR2KDM4EALDH1A1MAOA
SCHEMBL11882012 0.78 MAPT (0.48) ESR1ESR2KDM4EALDH1A1MAPK1
SCHEMBL3771039 0.78 MTNR1A (0.45) ESR1ESR2MAOACA1CA12
SCHEMBL9579211 0.78 NR4A1 (0.46) ESR1ESR2KDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0212944-B1 MELT-PROCESSABLE AROMATIC COPOLYESTER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1992-04-08 EP disclosed
CN-1007063-B COPOLYESTER VENO FINE CHEMICAL IND LTD (JP) 1990-03-07 CN disclosed
US-4746721-A ENGINEERING PLASTICS KABUSHIKI KAISHA UENO SEIYAKU OYO KENKYUJO (JP) 1988-05-24 US disclosed
EP-0212944-A2 Melt-processable aromatic copolyester Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1987-03-04 EP disclosed
CN-86105004-A COPOLYESTER 1987-02-18 CN disclosed