Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 11/20 | 0.60 |
| ▸ | HSP90AB1 | P08238 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | HTR2B | P41595 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064793 | 0.83 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1LMNATRPA1CHRM1 | |
| SCHEMBL4065970 | 0.83 | HSP90AA1 (0.54) | HSP90AA1HSP90AB1LMNATRPA1CHRM1 | |
| SCHEMBL21363250 | 0.82 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1LMNATRPA1CHRM1 | |
| SCHEMBL4241557 | 0.81 | APP (0.50) | HSP90AA1HSP90AB1LMNATRPA1CHRM1 | |
| SCHEMBL15313776 | 0.79 | CA1 (0.47) | HSP90AA1HSP90AB1LMNATRPA1CHRM1 | |
| SCHEMBL10653344 | 0.79 | BACE1 (0.52) | HSP90AA1HSP90AB1TRPA1ALDH1A1GAA | |
| SCHEMBL14283893 | 0.79 | BACE1 (0.55) | LMNATRPA1ALDH1A1GAABACE1 | |
| SCHEMBL21176787 | 0.78 | LMNA (0.50) | HSP90AA1HSP90AB1LMNATRPA1CHRM1 | |
| SCHEMBL4069702 | 0.78 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1LMNATRPA1CHRM1 | |
| SCHEMBL4060757 | 0.77 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1LMNATRPA1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11713335-B2 | Aminocoumarin compounds and methods of their use | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11713335-B2 | Aminocoumarin compounds and methods of their use | AAAS, PROC, AADAC | HSP90AA1 1344/4885HSP90AB1 1341/4885LMNA 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.