Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17119519 | 0.80 | KDM4E (0.43) | NQO2MTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL15032056 | 0.76 | HTR7 (0.45) | NQO2MTNR1AMTNR1BHTR7KDM4C | |
| SCHEMBL8246440 | 0.76 | HTR7 (0.45) | NQO2MTNR1AMTNR1BHTR7KDM4C | |
| SCHEMBL2594098 | 0.76 | NQO2 (0.42) | NQO2MTNR1AMTNR1BMAPTMAPK14 | |
| SCHEMBL11659645 | 0.74 | PPARG (0.45) | NQO2MTNR1AMTNR1BKDM4C | |
| SCHEMBL8430589 | 0.74 | HTR7 (0.43) | NQO2MTNR1AMTNR1BHTR7ACHE | |
| SCHEMBL7571658 | 0.73 | DPP9 (0.40) | NQO2MTNR1AMTNR1BHTR7KDM4C | |
| SCHEMBL14155148 | 0.71 | HTR7 (0.40) | NQO2MTNR1AMTNR1BHTR7KDM4C | |
| SCHEMBL8253224 | 0.71 | HTR7 (0.40) | NQO2MTNR1AMTNR1BHTR7KDM4C | |
| SCHEMBL27708787 | 0.70 | LMNA (0.36) | NQO2MTNR1AMTNR1BHTR7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571497-A2 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | Sanford-Burnham Medical Research Institute (US) | 2013-03-27 | — | — | EP | claimed |
| CN-103002887-A | Methods and compositions relating to retinoid receptor selective pathways | SANFORD BURNHAM MED RES INST | 2013-03-27 | — | — | CN | claimed |
| WO-2011140525-A2 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-11-10 | — | — | WO | claimed |
| CN-107050007-B | Methods and compositions relating to retinoid receptor selective pathways | 桑福德 - 伯纳姆医学研究所 | 2020-06-30 | — | — | CN | disclosed |
| US-10087156-B2 | Methods and compositions related to retinoid receptor-selective pathway | Sanford Burnham Prebys Medical Discovery Institute (US) | 2018-10-02 | — | — | US | disclosed |
| EP-2571497-B1 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | SANFORD BURNHAM MED RES INST (US) | 2018-09-19 | — | — | EP | disclosed |
| US-20170313668-A1 | METHODS AND COMPOSITIONS RELATED TO RETINOID RECEPTOR-SELECTIVE PATHWAY | Sanford Burnham Prebys Medical Discovery Institute | 2017-11-02 | — | — | US | disclosed |
| US-20170313668-A1 | METHODS AND COMPOSITIONS RELATED TO RETINOID RECEPTOR-SELECTIVE PATHWAY | Sanford Burnham Prebys Medical Discovery Institute | 2017-11-02 | — | — | US | disclosed |
| US-20170313668-A1 | METHODS AND COMPOSITIONS RELATED TO RETINOID RECEPTOR-SELECTIVE PATHWAY | Sanford Burnham Prebys Medical Discovery Institute | 2017-11-02 | — | — | US | disclosed |
| US-9611235-B2 | Methods and compositions related to a retinoid receptor-selective pathway | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2017-04-04 | — | — | US | disclosed |
| US-9611235-B2 | Methods and compositions related to a retinoid receptor-selective pathway | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2017-04-04 | — | — | US | disclosed |
| US-9611235-B2 | Methods and compositions related to a retinoid receptor-selective pathway | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2017-04-04 | — | — | US | disclosed |
| US-20150266842-A1 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | US ARMY, SECRETARY OF THE ARMY | 2015-09-24 | — | — | US | disclosed |
| US-20150266842-A1 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | US ARMY, SECRETARY OF THE ARMY | 2015-09-24 | — | — | US | disclosed |
| US-20150266842-A1 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | US ARMY, SECRETARY OF THE ARMY | 2015-09-24 | — | — | US | disclosed |
| EP-2571497-A2 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | Sanford-Burnham Medical Research Institute (US) | 2013-03-27 | — | — | EP | disclosed |
| CN-103002887-A | Methods and compositions relating to retinoid receptor selective pathways | SANFORD BURNHAM MED RES INST | 2013-03-27 | — | — | CN | disclosed |
| WO-2011140525-A2 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313668-A1 | METHODS AND COMPOSITIONS RELATED TO RETINOID RECEPTOR-SELECTIVE PATHWAY | RXRG, RXRB, RXRA | NQO2 3355/4885MTNR1A 574/4885MTNR1B 954/4885 |
| US-10087156-B2 | Methods and compositions related to retinoid receptor-selective pathway | RXRG, RXRB, RXRA | NQO2 3355/4885MTNR1A 574/4885MTNR1B 954/4885 |
| US-20150266842-A1 | METHODS AND COMPOSITIONS RELATED TO A RETINOID RECEPTOR-SELECTIVE PATHWAY | RXRG, RXRB, RXRA | NQO2 2156/4885MTNR1A 399/4885MTNR1B 848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.