Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 6/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636677 | 0.87 | CHRM3 (0.48) | CHRM3NPSR1RAB9ACHRM2CHRM1 | |
| SCHEMBL25907218 | 0.84 | CHRM3 (0.42) | CHRM3PPARGNCOA1NPSR1NCOA3 | |
| SCHEMBL2654268 | 0.74 | ALDH1A1 (0.41) | CHRM3NPSR1RAB9ACHRM2CHRM1 | |
| SCHEMBL7374418 | 0.74 | NPSR1 (0.41) | CHRM3NPSR1RAB9ACHRM2CHRM1 | |
| SCHEMBL11468485 | 0.72 | RAB9A (0.41) | CHRM3NPSR1RAB9AMAPTCHRM2 | |
| SCHEMBL11314832 | 0.71 | TSHR (0.39) | CHRM3NPSR1RAB9ACHRM2CHRM1 | |
| SCHEMBL826276 | 0.71 | CHRM3 (0.49) | CHRM3RAB9ACHRM2CHRM1POLB | |
| SCHEMBL2652613 | 0.70 | CHRM2 (0.41) | CHRM3NPSR1RAB9AMAPTCHRM2 | |
| SCHEMBL7371709 | 0.70 | KCNN4 (0.41) | CHRM3NPSR1RAB9ACHRM2CHRM1 | |
| SCHEMBL28025273 | 0.69 | CHRM3 (0.51) | CHRM3NPSR1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4219485-A1 | FUSED TRICYCLIC DERIVATIVE AND PHARMACEUTICAL APPLICATION THEREOF | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2023-08-02 | — | — | EP | disclosed |