Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | BMX | P51813 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25900587 | 0.75 | TIPARP (0.40) | HDAC1HDAC8HDAC6HDAC5CHEK1 | |
| SCHEMBL30617770 | 0.73 | BRD4 (0.42) | GAACDK2BRD4MIF | |
| SCHEMBL6913488 | 0.71 | ALDH1A1 (0.42) | ALDH1A1GAAL3MBTL1RAB9APKM | |
| SCHEMBL6906118 | 0.71 | ALDH1A1 (0.42) | ALDH1A1GAAL3MBTL1RAB9APKM | |
| SCHEMBL25908336 | 0.70 | MAPKAPK2 (0.32) | CHEK1AURKANTRK1CDK1IGF1R | |
| SCHEMBL25907600 | 0.70 | TIPARP (0.50) | HDAC1HDAC8HDAC6HDAC5CHEK1 | |
| SCHEMBL25903813 | 0.70 | BRD9 (0.37) | HDAC1HDAC8HDAC6HDAC5BRD4 | |
| SCHEMBL26800820 | 0.69 | BRD4 (0.39) | GAACDK2BRD4MIF | |
| SCHEMBL7521846 | 0.68 | ALDH1A1 (0.37) | ALDH1A1GAAL3MBTL1RAB9APKM | |
| SCHEMBL30130331 | 0.68 | ALDH1A1 (0.37) | ALDH1A1GAAL3MBTL1RAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023147418-A1 | PARP7 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2023-08-03 | — | — | WO | disclosed |