SCHEMBL25908358

SCHEMBL25908358

COc1ccc(C2(c3ccc(O)cc3)C(=O)N(C)c3ccccc32)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.56
GPR55 Q9Y2T6 3/20 0.56
PKM P14618 2/20 0.56
ADAMTS5 Q9UNA0 1/20 0.46
ALDH1A1 P00352 3/20 0.44
TSHR P16473 1/20 0.44
SCN9A Q15858 2/20 0.44
BACE1 P56817 1/20 0.42
BACE2 Q9Y5Z0 1/20 0.42
RAB9A P51151 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB2 P47870 1/20 0.42
MAPT P10636 4/20 0.42
CHRM2 P08172 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
KCNH2 Q12809 1/20 0.40
HTT P42858 1/20 0.40
GPR35 Q9HC97 1/20 0.40
KDM4E B2RXH2 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16155483 0.93 ADAMTS5 (0.51) CNR1GPR55PKMADAMTS5ALDH1A1
SCHEMBL492340 0.90 GPR55 (0.67) CNR1GPR55PKMALDH1A1TSHR
SCHEMBL29394877 0.90 GPR55 (0.67) CNR1GPR55PKMALDH1A1TSHR
SCHEMBL13471422 0.85 CNR1 (0.72) CNR1GPR55PKMADAMTS5ALDH1A1
SCHEMBL11929623 0.80 MAPT (0.56) CNR1GPR55PKMALDH1A1TSHR
SCHEMBL28250866 0.78 ADAMTS5 (0.50) PKMADAMTS5ALDH1A1TSHRSCN9A
SCHEMBL14999582 0.78 CNR1 (0.49) CNR1GPR55PKMADAMTS5ALDH1A1
SCHEMBL29489129 0.77 NT5E (0.43) CNR1GPR55PKMADAMTS5ALDH1A1
SCHEMBL14634509 0.77 NT5E (0.43) CNR1GPR55PKMADAMTS5ALDH1A1
SCHEMBL28770274 0.77 ADAMTS5 (0.49) PKMADAMTS5ALDH1A1TSHRSCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230244147-A1 COMPOSITION FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND AND POLYMER FOR FORMING ORGANIC FILM SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230244147-A1 COMPOSITION FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND COMPOUND AND POLYMER FOR FORMING ORGANIC FILM OR10J3, PYM1, AP1M1 CNR1 2565/4885GPR55 4460/4885PKM 2024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.