⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25800525 | 0.84 | — | — | |
| SCHEMBL25799314 | 0.76 | KDM4E (0.41) | — | |
| SCHEMBL22282139 | 0.74 | — | — | |
| SCHEMBL24521429 | 0.74 | KDM4E (0.33) | — | |
| SCHEMBL27011130 | 0.71 | — | — | |
| SCHEMBL27102760 | 0.71 | KDM4E (0.32) | — | |
| SCHEMBL16474365 | 0.71 | GABRA1 (0.40) | — | |
| SCHEMBL13524879 | 0.71 | CYP11B2 (0.39) | — | |
| SCHEMBL24521478 | 0.69 | — | — | |
| SCHEMBL27011242 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |