Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11581910 | 0.76 | PRKCG (0.39) | — | |
| SCHEMBL24521478 | 0.74 | — | — | |
| SCHEMBL13174575 | 0.73 | CYP11B2 (0.40) | DRD4DRD2DRD1 | |
| SCHEMBL13174599 | 0.68 | CYP11B2 (0.43) | DRD4DRD2DRD1 | |
| SCHEMBL8276421 | 0.67 | KDM4E (0.46) | KDM4E | |
| SCHEMBL21036162 | 0.67 | CYP11B2 (0.42) | DRD4DRD2DRD1 | |
| SCHEMBL22923562 | 0.65 | DRD2 (0.33) | DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL11161014 | 0.64 | KDM4E (0.59) | KDM4E | |
| SCHEMBL24457971 | 0.64 | PRKCG (0.32) | — | |
| SCHEMBL24457965 | 0.64 | PTGS2 (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146991-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |
| EP-3596072-B1 | PYRAZOLOCHLOROPHENYL COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2022-06-22 | — | — | EP | disclosed |