Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001814 | 0.71 | GPR119 (0.31) | — | |
| SCHEMBL2811594 | 0.67 | KDM4E (0.34) | MEN1KMT2A | |
| SCHEMBL17376305 | 0.66 | GPR119 (0.33) | MEN1KMT2A | |
| SCHEMBL17376242 | 0.66 | PLAT (0.34) | — | |
| SCHEMBL28901649 | 0.64 | HPGD (0.47) | — | |
| SCHEMBL2588754 | 0.64 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL31544790 | 0.64 | GPR119 (0.33) | MEN1KMT2A | |
| SCHEMBL31566810 | 0.64 | HSD17B10 (0.35) | — | |
| SCHEMBL3243883 | 0.62 | GPR119 (0.33) | MEN1KMT2A | |
| SCHEMBL2392461 | 0.62 | CHRM2 (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563780-A1 | 3, 3 -DISUBSTITUTED- ( 8 - AZA - BICYCLO [3.2.1]OCT- 8 - YL) -[5- (1H - PYRAZOL - 4 -YL) -THIOPHEN-3 -YL]METHANONES AS INHIBITORS OF 11 (BETA) -HSD1 | THE UNIVERSITY OF EDINBURGH (GB) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011135276-A1 | 3, 3 -DISUBSTITUTED- ( 8 - AZA - BICYCLO [3.2.1] OCT- 8 - YL) -[5- (1H - PYRAZOL - 4 -YL) -THIOPHEN-3 -YL] METHANONES AS INHIBITORS OF 11 (BETA) -HSD1 | THE UNIVERSITY OF EDINBURGH (GB) | 2011-11-03 | — | — | WO | disclosed |