SCHEMBL25909

SCHEMBL25909

O=c1[c]cc2ccccc2o1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.48
CA9 Q16790 6/20 0.48
CA1 P00915 4/20 0.48
CA2 P00918 3/20 0.48
CA3 P07451 3/20 0.48
CA4 P22748 3/20 0.48
CA6 P23280 3/20 0.48
CA5A P35218 3/20 0.48
CA7 P43166 3/20 0.48
CA14 Q9ULX7 3/20 0.48
CA5B Q9Y2D0 3/20 0.48
LMNA P02545 1/20 0.48
MCL1 Q07820 1/20 0.48
SOST Q9BQB4 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
HPGD P15428 3/20 0.42
SMN1; SMN2 Q16637 3/20 0.42
TYR P14679 1/20 0.42
DAO P14920 1/20 0.42
AKR1B1 P15121 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12612026 0.75
SCHEMBL12612153 0.75
SCHEMBL7705075 0.75 KDM4E (0.46) CA12CA9CA1MCL1TDP1
SCHEMBL1490958 0.72 CA9 (0.56) CA12CA9CA1CA2MCL1
SCHEMBL9781958 0.72 ALDH1A1 (0.55) CA12CA9CA1CA2CA4
SCHEMBL9781726 0.69 CYP2A6 (0.58) CA12CA9CA1CA2CA3
SCHEMBL6031307 0.69 ALDH1A1 (0.60) CA12CA9CA1CA2CA3
Coumarin SCHEMBL3441294 0.65 CA12 (1.00) CA12CA9CA1CA2CA3
Coumarin SCHEMBL1038138 0.65 CA12 (1.00) CA12CA9CA1CA2CA3
Coumarin SCHEMBL29385611 0.65 CA12 (1.00) CA12CA9CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9357 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208927-A1 WNT SIGNALING PATHWAY INHIBITORS FOR TREATMENTS OF DISEASE UNIVERSITY OF MARYLAND, BALTIMORE 2024-06-27 US claimed
CN-114867719-B Pyrrolidine and piperidine compounds 柳韩洋行 2024-06-25 CN claimed
CN-117597336-A Halogen substituted amino aza-heteroaryl compounds as inhibitors of hematopoietic progenitor kinase 1 (HPK 1) 安大略省癌症研究所(OICR) 2024-02-23 CN claimed
CN-117327065-A Carbazole derivatives as dopamine D2/3 receptor modulators 北京大学 2024-01-02 CN claimed
CN-117304205-A Benzimidazole ternary fused ring compound, pharmaceutically acceptable salt thereof and application thereof 中国科学院广州生物医药与健康研究院 2023-12-29 CN claimed
CN-117304204-A Benzimidazole ternary fused ring compound, pharmaceutically acceptable salt thereof and application thereof 中国科学院广州生物医药与健康研究院 2023-12-29 CN claimed
US-11655233-B2 WNT signaling pathway inhibitors for treatments of disease UNIVERSITY OF MARYLAND, BALTIMORE (US) 2023-05-23 US claimed
US-11572384-B2 Unusual substrates of tubulin tyrosine ligase FORSCHUNGSVERBUND BERLIN E.V. (DE) 2023-02-07 US claimed
CN-114867719-A Pyrrolidine and piperidine compounds 柳韩洋行 2022-08-05 CN claimed
CN-114369179-A Photoinitiator composition, photocuring composition and product containing photoinitiator composition 江苏英力科技发展有限公司 2022-04-19 CN claimed
EP-0082217-A1 Ammonium salts, process for their preparation, pharmaceutical preparations containing them and their use CIBA-GEIGY AG (CH) 1983-06-29 EP claimed
EP-0077603-A1 Process and intermediates for production of benzothiazine carboxamides PFIZER INC. (US) 1983-04-27 EP claimed
EP-0000599-B1 ELECTRICALLY PHOTOSENSITIVE PARTICLES FOR PHOTOELECTROPHORETIC MIGRATION IMAGING PROCESSES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-02-02 EP claimed
US-4343943-A CARBACEPHALOSPORIN ANTIBIOTICS KYOWA HAKKO KOGYO CO., LTD. (JP) 1982-08-10 US claimed
US-4293626-A ORGANIC PIGMENT EASTMAN KODAK COMPANY (US) 1981-10-06 US claimed
US-4272595-A UNSATURATED NITRILE EASTMAN KODAK COMPANY (US) 1981-06-09 US claimed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed
EP-0000599-A1 Electrically photosensitive particles for photoelectrophoretic migration imaging processes EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-02-07 EP claimed
US-3993645-A Stilbene optical brighteners and compositions brightened therewith STERLING DRUG INC. (US) 1976-11-23 US claimed
US-3932301-A NYLON, POLYESTERS STERLING DRUG INC. (US) 1976-01-13 US claimed