Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | GLA | P06280 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | CASP7 | P55210 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.56 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6031307 | 0.74 | ALDH1A1 (0.60) | CA9KDM4EMEN1GLAGAA | |
| SCHEMBL1258966 | 0.73 | KDM4E (0.64) | CA9KDM4EMEN1GLAGAA | |
| Umbelliferone SCHEMBL29396070 | 0.72 | CA9 (1.00) | CA9KDM4EMEN1GLAGAA | |
| SCHEMBL25909 | 0.72 | CA12 (0.48) | CA9KDM4EGLAGAACA12 | |
| Umbelliferone SCHEMBL29624448 | 0.72 | CA9 (1.00) | CA9KDM4EMEN1GLAGAA | |
| Umbelliferone SCHEMBL22018 | 0.72 | CA9 (1.00) | CA9KDM4EMEN1GLAGAA | |
| Umbelliferone SCHEMBL11137587 | 0.72 | CA9 (1.00) | CA9KDM4EMEN1GLAGAA | |
| Umbelliferone SCHEMBL2767044 | 0.71 | CA9 (0.96) | CA9KDM4EMEN1GLAGAA | |
| Umbelliferone SCHEMBL27915972 | 0.71 | CA9 (0.96) | CA9KDM4EMEN1GLAGAA | |
| Umbelliferone SCHEMBL307982 | 0.71 | CA9 (0.96) | CA9KDM4EMEN1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11987598-B2 | E-selectin antagonist compounds, compositions, and methods of use | GLYCOMIMETICS, INC. (US) | 2024-05-21 | — | — | US | disclosed |
| US-20230097694-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2023-03-30 | — | — | US | disclosed |
| US-11332491-B2 | E-selectin antagonist compounds, compositions, and methods of use | GLYCOMIMETICS, INC. (US) | 2022-05-17 | — | — | US | disclosed |
| US-20210017215-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2021-01-21 | — | — | US | disclosed |
| US-10766916-B2 | E-selectin antagonist compounds, compositions, and methods of use | GLYCOMIMETICS, INC. (US) | 2020-09-08 | — | — | US | disclosed |
| US-20200157134-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2020-05-21 | — | — | US | disclosed |
| EP-3296310-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GlycoMimetics, Inc. (US) | 2018-03-21 | — | — | EP | disclosed |
| US-20180066006-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2018-03-08 | — | — | US | disclosed |
| EP-2928476-B1 | COMPOUNDS, COMPOSITIONS AND METHODS USING E-SELECTIN ANTAGONISTS FOR MOBILIZATION OF HEMATOPOIETIC CELLS | GLYCOMIMETICS INC (US) | 2018-02-14 | — | — | EP | disclosed |
| US-9867841-B2 | Compounds, compositions and methods using E-selectin antagonists for mobilization of hematopoietic cells | GLYCOMIMETICS, INC. (US) | 2018-01-16 | — | — | US | disclosed |
| EP-2928476-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USING E-SELECTIN ANTAGONISTS FOR MOBILIZATION OF HEMATOPOIETIC CELLS | GlycoMimetics, Inc. (US) | 2015-10-14 | — | — | EP | disclosed |
| US-9109002-B2 | E-selectin antagonist compounds, compositions, and methods of use | GLYCOMIMETICS, INC. (US) | 2015-08-18 | — | — | US | disclosed |
| US-20150110808-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2015-04-23 | — | — | US | disclosed |
| WO-2015048616-A1 | METHODS AND COMPOSITIONS FOR TREATING AND/OR PREVENTING MUCOSITIS | GLYCOMIMETICS, INC. (US) | 2015-04-02 | — | — | WO | disclosed |
| EP-2794626-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GlycoMimetics, Inc. (US) | 2014-10-29 | — | — | EP | disclosed |
| WO-2014089269-A1 | COMPOUNDS, COMPOSITIONS AND METHODS USING E-SELECTIN ANTAGONISTS FOR MOBILIZATION OF HEMATOPOIETIC CELLS | GLYCOMIMETICS, INC. (US) | 2014-06-12 | — | — | WO | disclosed |
| WO-2013096926-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GLYCOMIMETICS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |
| US-20120214996-A1 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-08-23 | — | — | US | disclosed |
| EP-2477698-A2 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | Centre National de la Recherche Scientifique (FR) | 2012-07-25 | — | — | EP | disclosed |
| WO-2011033115-A2 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11332491-B2 | E-selectin antagonist compounds, compositions, and methods of use | SELE, SELPLG, SELP | CA9 2265/4885KDM4E 3628/4885MEN1 1506/4885 |
| US-20210017215-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SELE, SELPLG, SELP | CA9 2265/4885KDM4E 3628/4885MEN1 1506/4885 |
| US-10766916-B2 | E-selectin antagonist compounds, compositions, and methods of use | SELE, SELPLG, SELP | CA9 2265/4885KDM4E 3628/4885MEN1 1506/4885 |
| US-11987598-B2 | E-selectin antagonist compounds, compositions, and methods of use | SELE, SELPLG, SELP | CA9 2265/4885KDM4E 3628/4885MEN1 1506/4885 |
| US-20180066006-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SELE, SELPLG, SELP | CA9 2265/4885KDM4E 3628/4885MEN1 1506/4885 |
| US-20150110808-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SELE, SELPLG, SELP | CA9 2265/4885KDM4E 3628/4885MEN1 1506/4885 |
| US-20230097694-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SELE, SELPLG, SELP | CA9 2265/4885KDM4E 3628/4885MEN1 1506/4885 |
| US-20200157134-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | SELE, SELPLG, SELP | CA9 2265/4885KDM4E 3628/4885MEN1 1506/4885 |
| US-20120214996-A1 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | TST, PDXK, TBCB | CA9 4862/4885KDM4E 854/4885MEN1 4710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.