SCHEMBL25910341

SCHEMBL25910341

C/C(=C\c1cccc(/C=C(\C)c2ccc(C)cc2)c1)c1ccc(C)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 10/20 0.49
NQO2 P16083 6/20 0.48
PTGS2 P35354 6/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
ALOX5 P09917 1/20 0.46
NPC1 O15118 1/20 0.45
POLB P06746 1/20 0.45
MAPT P10636 1/20 0.45
RAB9A P51151 1/20 0.45
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
HIF1A Q16665 1/20 0.42
CYP1B1 Q16678 1/20 0.41
NFE2L2 Q16236 1/20 0.39
RARB P10826 2/20 0.39
RARG P13631 2/20 0.39
RARA P10276 1/20 0.39
RXRA P19793 1/20 0.39
SLC9A1 P19634 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4602278 0.86 MAPT (0.59) PTGS1NQO2PTGS2ESR1ESR2
SCHEMBL18790028 0.83 ESR1 (0.68) PTGS1NQO2PTGS2ESR1ESR2
SCHEMBL6546605 0.83 ESR1 (0.68) PTGS1NQO2PTGS2ESR1ESR2
SCHEMBL6546795 0.81 TP53 (0.47) PTGS1NQO2PTGS2ESR1ESR2
SCHEMBL7217583 0.80 CYP2A6 (0.47) PTGS1NQO2PTGS2ESR1ESR2
SCHEMBL7217591 0.80 CYP2A6 (0.47) PTGS1NQO2PTGS2ESR1ESR2
SCHEMBL6547576 0.78 ESR1 (0.55) PTGS1NQO2PTGS2ESR1ESR2
SCHEMBL7803180 0.76 ESR1 (0.64) PTGS1NQO2PTGS2ESR1ESR2
SCHEMBL23332030 0.74 ESR1 (0.52) PTGS1NQO2PTGS2ESR1ESR2
SCHEMBL6546772 0.74 NFE2L2 (0.46) PTGS1PTGS2ALOX5NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230241597-A1 PLATFORM FOR THE RECOVERY OF TRANSITION METAL CATALYSTS TEXAS TECH UNIVERSITY SYSTEM 2023-08-03 US disclosed