Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18573257 | 0.89 | CHRNB2 (0.44) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL28730797 | 0.84 | MEN1 (0.38) | KDM4EMAPK1HIF1AADRA1APSEN1 | |
| SCHEMBL2802696 | 0.83 | CCR2 (0.34) | KDM4EMAPK1HIF1AALDH1A1CCR2 | |
| SCHEMBL11278512 | 0.78 | DPP7 (0.35) | KDM4EMAPK1HIF1APAOXALDH1A1 | |
| SCHEMBL18289808 | 0.77 | KDM4E (0.44) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL4762361 | 0.76 | KDM4E (0.61) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL25911265 | 0.76 | KDM4E (0.56) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL30639002 | 0.75 | CHRNB2 (0.46) | TSHRALDH1A1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL14492895 | 0.75 | KDM4E (0.54) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL4761459 | 0.75 | KDM4E (0.54) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3304058-B1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | HARVARD COLLEGE (US) | 2023-08-02 | — | — | EP | disclosed |