SCHEMBL25911561

SCHEMBL25911561

CCCCCCCCCCCCCCCCCCOCCOP(=O)(O)OC[C@H]1O[C@@](C=N)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 6/20 0.36
▸ POLRMT O00411 1/20 0.35
▸ ENTPD1 P49961 2/20 0.33
▸ TRPM2 O94759 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25970314 0.89 ADK (0.38) ADKPOLRMTENTPD1TRPM2
SCHEMBL25959790 0.88 ADK (0.38) ADKPOLRMTENTPD1
SCHEMBL24407366 0.88 ADK (0.38) ADKPOLRMTENTPD1
SCHEMBL25957154 0.88 ADK (0.38) ADKPOLRMTENTPD1
SCHEMBL24339532 0.88 ADK (0.38) ADKPOLRMTENTPD1
SCHEMBL24407249 0.88 ADK (0.38) ADKPOLRMTENTPD1
SCHEMBL24407367 0.88 ADK (0.38) ADKPOLRMTENTPD1
SCHEMBL24340445 0.88 ADK (0.38) ADKPOLRMTENTPD1
SCHEMBL24407392 0.88 ADK (0.38) ADKPOLRMTENTPD1
SCHEMBL25957217 0.88 ADK (0.38) ADKPOLRMTENTPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230233593-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS VenatoRx Pharmaceuticals, Inc. 2023-07-27 — — US disclosed
US-11638715-B2 Orally-bioavailable nucleoside analogs VenatoRx Pharmaceuticals, Inc. (US) 2023-05-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11638715-B2 Orally-bioavailable nucleoside analogs SLC29A2, SLC29A1, PNP ADK 261/4885POLRMT 138/4885ENTPD1 44/4885
US-20230233593-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS SLC29A2, SLC29A1, PNP ADK 261/4885POLRMT 138/4885ENTPD1 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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