SCHEMBL25970314

SCHEMBL25970314

CCCCCCCCCCCCCCCCOCCCOP(=O)(O)OC[C@H]1O[C@@](C=NC)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ADK P55263 6/20 0.38
▸ POLRMT O00411 1/20 0.37
▸ FGFR1 P11362 1/20 0.35
▸ TRPM2 O94759 1/20 0.35
▸ ENTPD1 P49961 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25970034 0.90 POLRMT (0.36) ADKPOLRMT
SCHEMBL25911561 0.89 ADK (0.36) ADKPOLRMTTRPM2ENTPD1
SCHEMBL24304969 0.88 ADK (0.36) ADKPOLRMT
SCHEMBL26327604 0.88 POLRMT (0.35) ADKPOLRMTENTPD1
SCHEMBL25970023 0.87 ADK (0.39) ADKPOLRMTFGFR1TRPM2
SCHEMBL25970025 0.87 ADK (0.39) ADKPOLRMTFGFR1TRPM2
SCHEMBL24407327 0.87 ADK (0.39) ADKPOLRMTFGFR1TRPM2
SCHEMBL25974819 0.87 ADK (0.39) ADKPOLRMTFGFR1TRPM2
SCHEMBL25974764 0.87 ADK (0.39) ADKPOLRMTFGFR1TRPM2
SCHEMBL25975120 0.87 ADK (0.39) ADKPOLRMTFGFR1TRPM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 — — US disclosed
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030904-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 ADK 1238/4885POLRMT 371/4885FGFR1 4843/4885
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 ADK 1238/4885POLRMT 371/4885FGFR1 4843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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