Leu-Ala

Leu-Ala

SCHEMBL259116

CC(C)C[C@H](N)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.59
SLC1A3 P43003 1/20 0.47
SLC1A2 P43004 1/20 0.47
ACE P12821 7/20 0.46
MME P08473 1/20 0.46
CPA1 P15085 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
LARS1 Q9P2J5 1/20 0.45
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
LAP3 P28838 2/20 0.41
ANPEP P15144 2/20 0.41
RNPEP Q9H4A4 2/20 0.41
DNPEP Q9ULA0 1/20 0.41
SCN9A Q15858 3/20 0.40
CTSD P07339 1/20 0.40
BACE1 P56817 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Leu-Ala SCHEMBL14117889 1.00 SLC7A5 (0.59) SLC7A5SLC1A3SLC1A2ACEMME
Leu-Ala SCHEMBL31696288 1.00 SLC7A5 (0.59) SLC7A5SLC1A3SLC1A2ACEMME
Leu-Ala SCHEMBL259115 1.00 SLC7A5 (0.59) SLC7A5SLC1A3SLC1A2ACEMME
Leu-Ala SCHEMBL29531953 1.00 SLC7A5 (0.59) SLC7A5SLC1A3SLC1A2ACEMME
Leu-Ala SCHEMBL14831225 1.00 SLC7A5 (0.59) SLC7A5SLC1A3SLC1A2ACEMME
Leu-Ala SCHEMBL2030930 1.00 SLC7A5 (0.59) SLC7A5SLC1A3SLC1A2ACEMME
Leu-Ala SCHEMBL16863492 0.98 SLC7A5 (0.57) SLC7A5SLC1A3SLC1A2ACEMME
Leu-Ala SCHEMBL3677363 0.98 SLC7A5 (0.57) SLC7A5SLC1A3SLC1A2ACEMME
SCHEMBL30905089 0.96 SLC7A5 (0.55) SLC7A5SLC1A3SLC1A2ACEMME
SCHEMBL29967576 0.96 SLC7A5 (0.55) SLC7A5SLC1A3SLC1A2ACEMME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12566161-B2 Methods and consumer products for detecting a metabolite KIMBERLY-CLARK WORLDWIDE, INC. (US) 2026-03-03 US claimed
CN-119355268-A Application of two dipeptides in preparation of kit for diagnosing and distinguishing prostate cancer and benign prostatic hyperplasia 中国药科大学 2025-01-24 CN claimed
US-20250027938-A1 METABOLIC SIGNATURE FOR PREDICTION OF MUCOSAL INFLAMMATION AND MICROBIAL COMPOSITION IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2025-01-23 US claimed
EP-4483959-A2 NOVEL PEPTIDE COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF EYEBIO KOREA (KR) 2025-01-01 EP claimed
EP-4424365-A2 PET FOOD COMPOSITIONS Hill's Pet Nutrition, Inc. (US) 2024-09-04 EP claimed
EP-4017281-B1 PET FOOD COMPOSITIONS HILLS PET NUTRITION INC (US) 2024-08-28 EP claimed
US-12050228-B2 Automated sample quality assessment METABOLON, INC. (US) 2024-07-30 US claimed
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof EYEBIO KOREA (KR) 2024-07-11 US claimed
WO-2024132725-A1 SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF INTRACRANIAL HEMORRHAGIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF INTRACRANIAL HEMORRHAGIC STROKE FROM ACUTE ISCHEMIC STROKE UNIWERSYTET GDANSKI (PL) 2024-06-27 WO claimed
EP-4370919-A1 METABOLIC SIGNATURE FOR PREDICTION OF MUCOSAL INFLAMMATION AND MICROBIAL COMPOSITION Imperial College Innovations Limited (GB) 2024-05-22 EP claimed
US-20180275144-A1 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE PHARNEXT (FR) 2018-09-27 US claimed
WO-2016124574-A1 DIAGNOSTIC TOOLS FOR ALZHEIMER'S DISEASE PHARNEXT (FR) 2016-08-11 WO claimed
US-20160016929-A1 PRO-DRUG COMPOUNDS PROXIMAGEN LIMITED 2016-01-21 US claimed
EP-2970226-A1 PRO-DRUG COMPOUNDS Proximagen Limited (GB) 2016-01-20 EP claimed
WO-2014140510-A1 PRO-DRUG COMPOUNDS PROXIMAGEN LIMITED (GB) 2014-09-18 WO claimed
EP-0412061-B1 2-(N-acyl)amino-6,7-dimethoxy tetralines, process for their preparation and pharmaceutical compositions having antihypertensive activity containing same SIGMA TAU IND FARMACEUTI (IT) 1994-10-05 EP claimed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP claimed
EP-0412061-A2 2-(N-acyl)amino-6,7-dimethoxy tetralines, process for their preparation and pharmaceutical compositions having antihypertensive activity containing same Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) 1991-02-06 EP claimed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US claimed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228538-A1 Novel Peptide Compound Or Pharmaceutically Acceptable Salt Thereof VIP, NPPA, NGLY1 SLC7A5 129/4885SLC1A3 682/4885SLC1A2 2005/4885
US-20160016929-A1 PRO-DRUG COMPOUNDS H1-0, ZYX, FURIN SLC7A5 723/4885SLC1A3 1278/4885SLC1A2 2146/4885
US-12566161-B2 Methods and consumer products for detecting a metabolite SLC6A6, SLC7A11, CTH SLC7A5 40/4885SLC1A3 75/4885SLC1A2 102/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.