Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 6/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA4 | P22748 | 2/20 | 0.52 |
| ▸ | CA6 | P23280 | 2/20 | 0.52 |
| ▸ | CA5A | P35218 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21265229 | 0.83 | CA12 (0.46) | LMNACA12CA7CA9CA14 | |
| SCHEMBL19233346 | 0.78 | KDM4E (0.42) | LMNACA12CA7CA9CA14 | |
| SCHEMBL21248123 | 0.77 | HCAR2 (0.41) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL357565 | 0.73 | HCAR2 (0.89) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL337503 | 0.73 | HCAR2 (0.89) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL337504 | 0.73 | HCAR2 (0.89) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL1092833 | 0.73 | LMNA (0.70) | LMNAAKR1B10AKR1B1CA12CA4 | |
| SCHEMBL13552179 | 0.73 | LMNA (0.93) | LMNAAKR1B10AKR1B1CA12CA4 | |
| Benzyl Cinnamate SCHEMBL43213 | 0.73 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA4 | |
| Benzyl Cinnamate SCHEMBL43212 | 0.73 | LMNA (1.00) | LMNAAKR1B10AKR1B1CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |