Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 4/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5526838 | 0.86 | MAPT (0.42) | QPCTMAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL31143361 | 0.84 | MAPT (0.50) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL6008269 | 0.84 | MAPT (0.50) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL13373351 | 0.81 | ALDH1A1 (0.46) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL13373486 | 0.81 | PARP1 (0.46) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL2457365 | 0.79 | QPCT (0.50) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL28178021 | 0.77 | PARP1 (0.46) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL7021134 | 0.77 | QPCT (0.49) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL28178019 | 0.77 | PSMD11 (0.49) | QPCTQPCTLMAPTKDM4EALDH1A1 | |
| SCHEMBL25912038 | 0.77 | PARP1 (0.46) | QPCTQPCTLMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116851-B1 | ANALOGS OF FEXARAMINE AND METHODS OF MAKING AND USING | SALK INST FOR BIOLOGICAL STUDI (US) | 2023-07-26 | — | — | EP | disclosed |