Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2595659 | 0.92 | ALDH1A1 (0.33) | ALDH1A1GAAHPGDHSD17B10POLB | |
| SCHEMBL2588218 | 0.87 | ALDH1A1 (0.33) | ALDH1A1GAAHPGDPPARG | |
| SCHEMBL15312973 | 0.87 | ALDH1A1 (0.33) | ALDH1A1GAAHPGDPPARG | |
| SCHEMBL1119900 | 0.87 | ALDH1A1 (0.36) | ALDH1A1GAAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL13228438 | 0.86 | ALDH1A1 (0.35) | ALDH1A1GAAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL1120023 | 0.85 | ALDH1A1 (0.34) | ALDH1A1GAAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL15446675 | 0.83 | ALDH1A1 (0.43) | ALDH1A1GAAHPGDHSD17B10POLB | |
| SCHEMBL29677 | 0.82 | CYP1A2 (0.34) | ALDH1A1GAAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL1119901 | 0.82 | ALDH1A1 (0.35) | ALDH1A1GAAHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL1119946 | 0.82 | GAA (0.45) | ALDH1A1GAAHPGDHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563786-B1 | Ketoheteroarylpiperidine and piperazine derivatives as fungicides | BAYER IP GMBH (DE) | 2016-11-02 | — | — | EP | disclosed |
| US-9357779-B2 | Ketoheteroarylpiperdine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-06-07 | — | — | US | disclosed |
| US-9220266-B2 | Ketoheteroarylpiperidine and -piperazine derivatives as fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-12-29 | — | — | US | disclosed |
| US-20130274292-A1 | Ketoheteroarylpiperdine and -Piperazine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2013-10-17 | — | — | US | disclosed |
| EP-2563786-A1 | KETOHETEROARYLPIPERIDINE AND KETOHETEROARYLPIPERAZINE DERIVATES AS FUNGICIDES | Bayer CropScience AG (DE) | 2013-03-06 | — | — | EP | disclosed |
| US-20110312999-A1 | Ketoheteroarylpiperidine and -Piperazine Derivatives as Fungicides | BAYER CROPSCIENCE AG (DE) | 2011-12-22 | — | — | US | disclosed |
| WO-2011134969-A1 | KETOHETEROARYLPIPERIDINE AND KETOHETEROARYLPIPERAZINE DERIVATES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274292-A1 | Ketoheteroarylpiperdine and -Piperazine Derivatives as Fungicides | CYP4Z1, CYP51A1, CYP1A1 | ALDH1A1 982/4885GAA 234/4885HPGD 808/4885 |
| US-20110312999-A1 | Ketoheteroarylpiperidine and -Piperazine Derivatives as Fungicides | CYP4Z1, CYP51A1, KCNH1 | ALDH1A1 792/4885GAA 209/4885HPGD 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.