Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 5/20 | 0.35 |
| ▸ | MAPK6 | Q16659 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.35 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30467033 | 0.85 | BRAF (0.35) | MAPK8IRAK4BRAFCSF1RPDGFRB | |
| SCHEMBL25913001 | 0.85 | BRAF (0.35) | MAPK8IRAK4BRAFCSF1RPDGFRB | |
| SCHEMBL25914331 | 0.82 | DYRK1A (0.35) | IRAK4BRAF | |
| SCHEMBL25912757 | 0.81 | P2RX3 (0.36) | MAPK8GSK3BMAPK6IRAK4BRAF | |
| SCHEMBL25912755 | 0.80 | MAPK8 (0.42) | MAPK8CDK4GSK3BPIK3C3MAPK6 | |
| SCHEMBL25911299 | 0.71 | CSF1R (0.52) | CSF1RPDGFRB | |
| SCHEMBL25913590 | 0.70 | CSF1R (0.43) | BRAFCSF1RPDGFRBMAPK10 | |
| SCHEMBL25912909 | 0.70 | PDGFRB (0.50) | BRAFCSF1RPDGFRBMAPK10 | |
| SCHEMBL25913399 | 0.69 | CSF1R (0.39) | BRAFCSF1RPDGFRB | |
| SCHEMBL16046266 | 0.69 | CSF1R (0.69) | CSF1RPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |