Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.55 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11891928 | 0.81 | HPGDS (0.55) | HPGDSP4HTMKDM4EALDH1A1TRPM8 | |
| SCHEMBL5415248 | 0.80 | MAPT (0.61) | L3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL1671397 | 0.79 | KDM4E (0.61) | HPGDSP4HTMKDM4EALDH1A1TDP1 | |
| SCHEMBL27589233 | 0.78 | MAPT (0.49) | KDM4EALDH1A1L3MBTL1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3216270 | 0.77 | HPGDS (0.59) | HPGDSP4HTMKDM4EALDH1A1TDP1 | |
| SCHEMBL3408513 | 0.77 | HPGDS (0.55) | HPGDSP4HTMKDM4ETDP1TP53 | |
| SCHEMBL3220170 | 0.77 | HPGDS (0.55) | HPGDSP4HTMKDM4EALDH1A1TDP1 | |
| SCHEMBL3217944 | 0.77 | HPGDS (0.55) | HPGDSP4HTMKDM4EALDH1A1TRPM8 | |
| Hydrochloric Acid SCHEMBL11027155 | 0.76 | HPGDS (0.54) | HPGDSP4HTMKDM4EALDH1A1TDP1 | |
| Propiophenone SCHEMBL7090411 | 0.73 | SMN1; SMN2 (0.72) | KDM4EALDH1A1TDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230190747-A1 | PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS | SANOFI SA (FR) | 2023-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230190747-A1 | PHENYLOXADIAZOLE DERIVATIVES AS PGDS INHIBITORS | PTGER1, PTGIS, PTGDR | HPGDS 6/4885P4HTM 1200/4885KDM4E 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.