Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 11/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.39 |
| ▸ | FLT3 | P36888 | 4/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 4/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914740 | 0.87 | CSF1R (0.35) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25911790 | 0.85 | CSF1R (0.53) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25910556 | 0.83 | PDGFRB (0.49) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25914665 | 0.82 | CSF1R (0.39) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25913387 | 0.82 | KCNH2 (0.35) | — | |
| SCHEMBL25912706 | 0.81 | CSF1R (0.43) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25914529 | 0.81 | GAA (0.41) | CSF1RPDGFRAFLT3PDGFRBLCK | |
| SCHEMBL25913446 | 0.80 | MAOA (0.35) | BRAFRAF1MAOBMEN1ALDH1A1 | |
| SCHEMBL25913040 | 0.77 | KDM4E (0.38) | BRAFALDH1A1SCN9A | |
| SCHEMBL25913396 | 0.76 | ESR2 (0.46) | PDGFRAPDGFRBMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |