Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914665 | 0.86 | CSF1R (0.39) | MAPTCYP3A4KDRCSF1RPDGFRB | |
| SCHEMBL25911790 | 0.84 | CSF1R (0.53) | KDRCSF1RPDGFRBLCKKIT | |
| SCHEMBL25914528 | 0.84 | GAA (0.45) | GAAMAPTTHRBCYP3A4MEN1 | |
| SCHEMBL25912706 | 0.83 | CSF1R (0.43) | MAPTKDRCSF1RPDGFRBLCK | |
| SCHEMBL25913399 | 0.81 | CSF1R (0.39) | MEN1KMT2AKDRCSF1RPDGFRB | |
| SCHEMBL25914718 | 0.80 | KDR (0.38) | GAAMAPTTHRBCYP3A4MEN1 | |
| SCHEMBL25914740 | 0.78 | CSF1R (0.35) | MAPTMEN1KMT2ACSF1RPDGFRB | |
| SCHEMBL25910288 | 0.78 | CSF1R (0.41) | MAPTCYP3A4MEN1KMT2AKDR | |
| SCHEMBL25913293 | 0.78 | CSF1R (0.52) | KDRCSF1RPDGFRBLCKKIT | |
| SCHEMBL25914852 | 0.77 | CSF1R (0.40) | KDRCSF1RPDGFRBLCKKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |