Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14336548 | 0.88 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL14336556 | 0.86 | CHEK2 (0.57) | SMN1; SMN2ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL14336559 | 0.84 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL14336565 | 0.84 | ALDH1A1 (0.78) | SMN1; SMN2ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL14336572 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL6113137 | 0.79 | HSP90AA1 (0.76) | SMN1; SMN2ALDH1A1KDM4EHSP90AA1ESR2 | |
| SCHEMBL17821410 | 0.78 | HSP90AA1 (0.51) | SMN1; SMN2ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL725578 | 0.78 | FABP6 (0.66) | SMN1; SMN2ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL18659837 | 0.77 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL22487928 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1L3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| EP-4215525-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373972-A1 | PIPERAZINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | F7, F11, HABP2 | SMN1; SMN2 4054/4885ALDH1A1 1218/4885L3MBTL1 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.