Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.49 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.49 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.49 |
| ▸ | CBFB | Q13951 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110612 | 0.85 | ALDH1A1 (0.57) | TDP1ALDH1A1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL27438068 | 0.84 | SMN1; SMN2 (0.54) | TDP1ALDH1A1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL5514158 | 0.83 | POLB (0.70) | ALDH1A1HSD17B10KMT2AMEN1MAPT | |
| SCHEMBL11798087 | 0.82 | ALDH1A1 (0.56) | TDP1ALDH1A1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL2336203 | 0.82 | POLB (0.68) | TDP1ALDH1A1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL29990241 | 0.82 | POLB (0.68) | TDP1ALDH1A1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL22374212 | 0.81 | PKM (0.54) | TDP1ALDH1A1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL5779177 | 0.79 | ALDH1A1 (0.53) | TDP1ALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL28477202 | 0.79 | SMN1; SMN2 (0.48) | TDP1ALDH1A1HSD17B10SMN1; SMN2HTT | |
| SCHEMBL30561861 | 0.79 | ALDH1A1 (0.53) | TDP1ALDH1A1SMN1; SMN2HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023144736-A1 | COMPOSITIONS FOR PREVENTING OR TREATING PULMONARY ARTERIAL HYPERTENSION | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-03 | — | — | WO | disclosed |
| WO-2023144737-A1 | COMPOSITIONS FOR PREVENTING OR TREATING HEART FAILURE (HF) | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2023-08-03 | — | — | WO | disclosed |