Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.47 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.47 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.47 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.47 |
| ▸ | CBFB | Q13951 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27438068 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2HTTL3MBTL1MEN1MAPT | |
| SCHEMBL11798087 | 0.81 | ALDH1A1 (0.56) | SMN1; SMN2HTTL3MBTL1MEN1MAPT | |
| SCHEMBL25914487 | 0.79 | TDP1 (0.53) | SMN1; SMN2HTTL3MBTL1MEN1MAPT | |
| SCHEMBL22374212 | 0.79 | PKM (0.54) | SMN1; SMN2HTTL3MBTL1MEN1MAPT | |
| SCHEMBL2339940 | 0.78 | TDP1 (0.55) | SMN1; SMN2HTTL3MBTL1MEN1MAPT | |
| SCHEMBL25914490 | 0.78 | MEN1 (0.50) | SMN1; SMN2HTTL3MBTL1MEN1MAPT | |
| SCHEMBL26386572 | 0.78 | RORC (0.51) | SMN1; SMN2HTTL3MBTL1MEN1MAPT | |
| SCHEMBL5779177 | 0.78 | ALDH1A1 (0.53) | SMN1; SMN2HTTL3MBTL1MEN1MAPT | |
| SCHEMBL30561861 | 0.78 | ALDH1A1 (0.53) | SMN1; SMN2HTTL3MBTL1MEN1MAPT | |
| SCHEMBL22451907 | 0.76 | MYC (0.53) | SMN1; SMN2HTTL3MBTL1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108499606-B | O-mercapto aryl nitrogen heterocyclic carbene metal complex catalyst and preparation method and application thereof | 万华化学集团股份有限公司 | 2020-11-20 | — | — | CN | disclosed |