Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAPDH | P04406 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569824 | 0.88 | — | — | |
| SCHEMBL3707104 | 0.81 | CDC25B (0.41) | — | |
| SCHEMBL989080 | 0.75 | BACE1 (0.47) | GAPDH | |
| SCHEMBL5613103 | 0.73 | — | — | |
| SCHEMBL795788 | 0.72 | MEN1 (0.30) | — | |
| SCHEMBL710125 | 0.71 | PTGS2 (0.34) | — | |
| SCHEMBL30502984 | 0.71 | PTGS2 (0.34) | — | |
| SCHEMBL26205055 | 0.69 | CDC25B (0.44) | GAPDH | |
| SCHEMBL27800017 | 0.69 | PTGS2 (0.33) | — | |
| SCHEMBL2591450 | 0.69 | NPC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3328851-A1 | FACTOR XIA MACROCYCLIC INHIBITORS BEARING ALKYL OR CYCLOALKYL P2' MOIETIES | Bristol-Myers Squibb Company (US) | 2018-06-06 | — | — | EP | disclosed |
| WO-2017019819-A1 | FACTOR XIA MACROCYCLIC INHIBITORS BEARING ALKYL OR CYCLOALKYL P2' MOIETIES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-02-02 | — | — | WO | disclosed |
| EP-2566869-A1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | Gilead Connecticut, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011140488-A1 | PYRIDONE AND AZA-PYRIDONE COMPOUNDS AND METHODS OF USE | GILEAD CONNECTICUT, INC. (US) | 2011-11-10 | — | — | WO | disclosed |
| US-5089374-A | Novel bis-onium salts and the use thereof as photoinitiators | EASTMAN KODAK COMPANY (US) | 1992-02-18 | — | — | US | disclosed |