Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19546024 | 0.77 | MAOA (0.47) | MAOAMAOB | |
| SCHEMBL8338768 | 0.77 | MAOA (0.47) | MAOAMAOB | |
| SCHEMBL3401455 | 0.75 | KMT2A (0.40) | CHRNB2CHRNB4CHRNA4CHRNA3 | |
| SCHEMBL30639002 | 0.73 | CHRNB2 (0.46) | CHRNB2CHRNB4CHRNA4CHRNA3 | |
| SCHEMBL6656744 | 0.72 | ALDH1A1 (0.40) | — | |
| SCHEMBL18573257 | 0.72 | CHRNB2 (0.44) | CHRNB2CHRNB4CHRNA4CHRNA3 | |
| SCHEMBL6656864 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL6661745 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL5309429 | 0.70 | CHRNB2 (0.35) | CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL17481296 | 0.69 | MAOA (0.53) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215527-A1 | COMPOSITIONS AND METHODS FOR TREATING RETINAL DEGRADATION | University Of Kentucky Research Foundation (US) | 2023-07-26 | — | — | EP | disclosed |