Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25914529 | 0.84 | GAA (0.41) | GAAMAPTTHRBCYP3A4ALDH1A1 | |
| SCHEMBL25914664 | 0.81 | ESR1 (0.38) | MAPTCYP3A4EGFR | |
| SCHEMBL31010902 | 0.80 | ESR1 (0.43) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL25317161 | 0.80 | ESR1 (0.43) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL25913145 | 0.80 | ESR1 (0.37) | CYP3A4KDR | |
| SCHEMBL25317059 | 0.77 | PDGFRB (0.47) | MAPTEGFR | |
| SCHEMBL25317420 | 0.77 | ESR1 (0.40) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL25914718 | 0.77 | KDR (0.38) | GAAMAPTTHRBCYP3A4ALDH1A1 | |
| SCHEMBL25913396 | 0.74 | ESR2 (0.46) | GAAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL25913124 | 0.73 | ESR1 (0.43) | GAAMAPTALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |